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Current developments in 3D bioprinting for tissue engineering

机译:用于组织工程的3D生物打印的最新发展

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摘要

The field of 3-dimensional (3D) bioprinting have enjoyed rapid development in the past few years for the applications in tissue engineering and regenerative medicine. In this review, we summarize the most updated developments in 3D bioprinting for the applications in the tissue engineering with a focus on the printable biomaterials used as bioinks. These developments include 1) novel printing regimes have been enabled by the use of fugitive inks for the creation of intricate structures e.g. vascularized tissue constructs; 2) mechanical strength of printed constructs can be enhanced by co-printing soft and hard biomaterials; 3) bioprinted in-vitro models for drug testing applications are closer to reality. We conclude that the research and application of new bioinks will remain the key highlights of the future developments in 3D bioprinting for tissue engineering.
机译:过去几年中,在组织工程和再生医学中的应用,3维(3D)生物打印领域得到了快速发展。在这篇综述中,我们总结了3D生物打印在组织工程中的最新发展,重点是用作生物墨水的可打印生物材料。这些发展包括:1)通过使用逃犯性墨水来创建复杂的结构,例如印刷机,实现了新颖的印刷方式。血管化的组织结构; 2)可以通过共同印刷软硬生物材料来增强印刷结构的机械强度; 3)用于药物测试应用的生物打印体外模型更加接近现实。我们得出的结论是,新的生物墨水的研究和应用将仍然是组织工程3D生物打印未来发展的重点。

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